David--good to see you back here again! Hope all is well with you.
With regard to your question, my suggestion would be to talk to a good villa rental agent, who has SEEN all the properties they handle. Only someone who has actually seen the property can verify that it is truly suitable for c/o use. You might try
www.gobeach.com. They are primarily St Maarten/ST. Martin, but they do handle other islands. They don't list Puerto Rico, but perhaps they can point you to someone who handles it. Best wishes!