West side is of course more sheltered from wave action. My personal preference is Marigot and Grand Case for good holding and proximity to restaurants/shopping. Anse Marcel is quieter with less ashore but very safe and pleasant. I don't really know the east that well, Zanshin will help with that I'm sure, but the one time I anchored overnight in Orient Bay wasn't a great experience as conditions changed in the middle of the night and became pretty uncomfortable.